Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.74 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857927 | 0.96 | USP2 (0.88) | USP2KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL11020028 | 0.87 | ALDH1A1 (0.85) | KDM4EPOLBL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL11017523 | 0.82 | ALDH1A1 (0.79) | USP2KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL30556324 | 0.81 | USP2 (0.65) | USP2KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL4855453 | 0.81 | USP2 (0.65) | USP2KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL14003353 | 0.81 | USP2 (0.65) | USP2KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL30556329 | 0.80 | USP2 (0.65) | USP2KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL4265430 | 0.80 | KDM4E (0.63) | USP2KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL14406119 | 0.80 | USP2 (0.64) | USP2KDM4EPOLBL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11617183 | 0.80 | USP2 (0.64) | USP2KDM4EPOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071559-A | Pharmaceutically active 2-omega-aminoalkoxydiphenyls | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-01-31 | — | — | US | disclosed |