Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665839 | 0.88 | MAPT (0.53) | MAPTCRHBPCRHR2L3MBTL1KCNH2 | |
| SCHEMBL11664713 | 0.87 | MAPT (0.48) | MAPTCRHBPCRHR2L3MBTL1KCNH2 | |
| SCHEMBL11665934 | 0.86 | MAPT (0.53) | MAPTCRHBPCRHR2L3MBTL1KCNH2 | |
| SCHEMBL14515262 | 0.86 | MAPT (0.53) | MAPTCRHBPCRHR2L3MBTL1KCNH2 | |
| SCHEMBL14515256 | 0.86 | MAPT (0.53) | MAPTCRHBPCRHR2L3MBTL1KCNH2 | |
| SCHEMBL11665109 | 0.84 | MAPT (0.49) | MAPTCRHBPCRHR2L3MBTL1KCNH2 | |
| SCHEMBL11664401 | 0.82 | RAB9A (0.42) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL11665607 | 0.77 | MAPT (0.49) | MAPTCRHBPCRHR2L3MBTL1KCNH2 | |
| SCHEMBL11666008 | 0.76 | AR (0.57) | MAPTCRHBPCRHR2L3MBTL1GAA | |
| SCHEMBL11665323 | 0.76 | MAPT (0.48) | MAPTCRHBPCRHR2KCNH2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123614-A | USED IN DETECTION AND MEASUREMENT OF BIOLOGICAL SYSTEMS AND/OR COMPONENTS | SYNTEX (U.S.A.) INC. (US) | 1978-10-31 | — | — | US | disclosed |