Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715309 | 0.84 | MAPT (0.54) | ARLTA4HSCN5ASCN9AHTR2A | |
| SCHEMBL19628791 | 0.82 | MAPT (0.52) | ARADAMTS5SCN5ASCN9AHTR2A | |
| SCHEMBL15635197 | 0.82 | PPARG (0.55) | ARTLR8TLR7LTA4HKIF11 | |
| SCHEMBL3716891 | 0.81 | MAOA (0.52) | ARSCN5ASCN9AHTR2ASLC6A4 | |
| SCHEMBL29349910 | 0.81 | MAOA (0.52) | ARSCN5ASCN9AHTR2ASLC6A4 | |
| SCHEMBL11648951 | 0.80 | FFAR1 (0.50) | AREPAS1P2RX4HTR2ASLC6A4 | |
| SCHEMBL6206121 | 0.80 | RHEB (0.52) | ARSCN5ASCN9AHTR2ASLC6A4 | |
| SCHEMBL29924283 | 0.80 | RHEB (0.52) | ARSCN5ASCN9AHTR2ASLC6A4 | |
| SCHEMBL9468022 | 0.80 | MRGPRX4 (0.53) | P2RX4SLC6A4 | |
| SCHEMBL11646474 | 0.79 | AR (0.48) | AREPAS1TLR8P2RX4P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124370-A | Diphenyl ethers for tobacco sucker control | ROHM AND HAAS COMPANY (US) | 1978-11-07 | — | — | US | disclosed |