Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11578139 | 0.92 | CNR2 (0.45) | LMNAMEN1ABCC4PKMPTGS1 | |
| SCHEMBL11579822 | 0.91 | CNR2 (0.50) | LMNAMEN1ABCC4PKMPTGS1 | |
| SCHEMBL11579496 | 0.90 | CNR2 (0.49) | LMNAMEN1ABCC4PKMPTGS1 | |
| SCHEMBL11557695 | 0.89 | LMNA (0.52) | LMNAMEN1ABCC4PKMPTGS1 | |
| SCHEMBL11579929 | 0.82 | LMNA (0.40) | LMNAMEN1ABCC4PKMPTGS1 | |
| SCHEMBL11580726 | 0.81 | KMT2A (0.42) | LMNAMEN1ABCC4PKMPTGS1 | |
| SCHEMBL10671020 | 0.80 | LMNA (0.43) | LMNAMEN1ABCC4PKMPTGS1 | |
| SCHEMBL11578367 | 0.77 | LMNA (0.43) | LMNAMEN1ABCC4PKMPTGS1 | |
| SCHEMBL11581691 | 0.76 | KDM4E (0.41) | LMNAMEN1ABCC4PKMPTGS1 | |
| SCHEMBL11579417 | 0.76 | KDM4E (0.41) | LMNAMEN1ABCC4PKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079060-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
| US-3997545-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-12-14 | — | — | US | disclosed |
| US-3951989-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-20 | — | — | US | disclosed |