Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27507309 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL818787 | 1.00 | TSHR (0.38) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL3673386 | 0.93 | TSHR (0.40) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL180874 | 0.93 | TSHR (0.40) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL78510 | 0.93 | TSHR (0.40) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL3671630 | 0.93 | TSHR (0.40) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL80551 | 0.93 | TSHR (0.40) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL7932503 | 0.90 | TSHR (0.35) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL3835334 | 0.90 | TSHR (0.32) | TSHRLMNA | |
| Octane SCHEMBL29076104 | 0.90 | TSHR (0.47) | TSHRTHRBDNM1TRPM8OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073820-A | TUNGSTEN COMPOUND-ALKYLALUMINUM HALIDE-AMINE CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-02-14 | — | — | US | disclosed |