SCHEMBL3835334

SCHEMBL3835334

CC(C)C[Al](CC(C)C)CC(C)C.CCCC[Al](CCCC)CCCC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9408974 0.92 TSHR (0.33) TSHRLMNA
SCHEMBL733085 0.92 TSHR (0.33) TSHRLMNA
SCHEMBL27507309 0.90 TSHR (0.38) TSHRLMNA
SCHEMBL818787 0.90 TSHR (0.38) TSHRLMNA
SCHEMBL11664749 0.90 TSHR (0.38) TSHRLMNA
SCHEMBL25231381 0.90 TSHR (0.32) TSHRLMNA
SCHEMBL7027626 0.90 TSHR (0.32) TSHRLMNA
SCHEMBL733084 0.90 TSHR (0.32) TSHRLMNA
Lithium Ion SCHEMBL7027624 0.87 OPRM1 (0.33) TSHR
Pentane SCHEMBL8679357 0.86 TSHR (0.44) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6943225-B2 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2005-09-13 US claimed
EP-0646137-B1 SUPPORTED CATALYST FOR 1-OLEFIN(S) (CO)POLYMERIZATION EXXON CHEMICAL PATENTS INC (US) 1996-12-18 EP claimed
EP-0646137-A1 SUPPORTED CATALYST FOR 1-OLEFIN(S) (CO)POLYMERIZATION. EXXON CHEMICAL PATENTS INC (US) 1995-04-05 EP claimed
WO-1993025586-A1 SUPPORTED CATALYST FOR 1-OLEFIN(S) (CO)POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1993-12-23 WO claimed
US-5238892-A Solid product formed by treating undehydrated support with hydrocarbon solution containing reacted transition metal metallocene and trialkylaluminum compound EXXON CHEMICAL PATENTS INC. (US) 1993-08-24 US claimed
US-20170066993-A1 Methods for Treating Substrates Prior to Metathesis Reactions, and Methods for Metathesizing Substrates ELEVANCE RENEWABLE SCIENCES, INC. (US) 2017-03-09 US disclosed
US-9388097-B2 Methods for treating substrates prior to metathesis reactions, and methods for metathesizing substrates ELEVANCE RENEWABLE SCIENCES, INC. (US) 2016-07-12 US disclosed
EP-2970774-A1 TREATED METATHESIS SUBSTRATE MATERIALS AND METHODS OF MAKING AND USING THE SAME Elevance Renewable Sciences, Inc. (US) 2016-01-20 EP disclosed
WO-2014160417-A1 TREATED METATHESIS SUBSTRATE MATERIALS AND METHODS OF MAKING AND USING THE SAME ELEVANCE RENEWABLE SCIENCES, INC. (US) 2014-10-02 WO disclosed
US-20140275595-A1 METHODS FOR TREATING SUBSTRATES PRIOR TO METATHESIS REACTIONS, AND METHODS FOR METATHESIZING SUBSTRATES ELEVANCE RENEWABLE SCIENCES, INC. (US) 2014-09-18 US disclosed
EP-1753794-B9 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2009-03-04 EP disclosed
EP-1753794-B1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2008-06-04 EP disclosed
EP-0368644-A1 Method for utilizing triethylaluminum to prepare an alumoxane support for an active metallocene catalyst EXXON CHEMICAL PATENTS INC. (US) 1990-05-16 EP disclosed
US-4925821-A SILICA GEL CATALYST SUPPORT EXXON CHEMICAL PATENTS INC. (US) 1990-05-15 US disclosed
EP-0367503-A1 Method for utilizing triethylaluminum to prepare an alumoxane support for an active metallocene catalyst EXXON CHEMICAL PATENTS INC. (US) 1990-05-09 EP disclosed
US-4912075-A Mixing silic gel with trialkyl aluminum and metallocene EXXON CHEMICAL PATENTS INC. (US) 1990-03-27 US disclosed
US-4904630-A COORDINATION CATALYST HAVING A SILICON COMPOUND IN PLACE OF AN ELECTRON DONOR; STEREOSPECIFIC; EFFICIENCY MITSUBISHI PETROCHEMICAL COMPANY LTD. (JP) 1990-02-27 US disclosed
EP-0336593-A1 Method for preparing a supported metallocene alumoxane catalyst EXXON CHEMICAL PATENTS INC. (US) 1989-10-11 EP disclosed
EP-0323716-A1 Method for preparing a supported metallocene-alumoxane catalyst for gas phase polymerization EXXON CHEMICAL PATENTS INC. (US) 1989-07-12 EP disclosed
EP-0299712-A2 Catalyst for olefin polymerization MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275595-A1 METHODS FOR TREATING SUBSTRATES PRIOR TO METATHESIS REACTIONS, AND METHODS FOR METATHESIZING SUBSTRATES MSMO1, APEX1, AKR7A2 TSHR 3896/4885LMNA 1537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.