Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665297 | 0.83 | CYP2C19 (0.33) | CYP2C19HTT | |
| SCHEMBL14552089 | 0.65 | APLNR (0.42) | CYP2C19CHRM2CHRM4CHRM3 | |
| SCHEMBL11660324 | 0.64 | NPSR1 (0.39) | — | |
| SCHEMBL15760366 | 0.62 | TSHR (0.31) | — | |
| SCHEMBL19649538 | 0.62 | ATM (0.34) | CHRM2CHRM4CHRM3 | |
| SCHEMBL22352876 | 0.62 | NPSR1 (0.34) | CHRM2CHRM4CHRM3HTT | |
| SCHEMBL25870290 | 0.62 | NPSR1 (0.34) | CHRM2CHRM4CHRM3HTT | |
| SCHEMBL19638369 | 0.62 | ATM (0.34) | CHRM2CHRM4CHRM3 | |
| SCHEMBL1231230 | 0.62 | GAA (0.47) | CYP2C19HTT | |
| SCHEMBL8494369 | 0.61 | CHRM2 (0.48) | CYP2C19CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093586-A | Pyrrolidine dicarboxylic acids and esters and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1978-06-06 | — | — | US | claimed |
| US-4093586-A | Pyrrolidine dicarboxylic acids and esters and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |