Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 3/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656259 | 0.95 | CACNA1C (0.57) | CACNA1CSCN5ADRD2HTR2AHTR2B | |
| SCHEMBL11056050 | 0.94 | SCN5A (0.55) | CACNA1CSCN5ADRD2HTR2AHTR2B | |
| SCHEMBL11060254 | 0.92 | SCN5A (0.59) | CACNA1CSCN5ADRD2HTR2AHTR2B | |
| SCHEMBL11053537 | 0.90 | DRD2 (0.48) | CACNA1CSCN5ADRD2HTR2AHTR2B | |
| SCHEMBL11272026 | 0.88 | CACNA1C (0.44) | CACNA1CSCN5ADRD2HTR2AHTR2B | |
| SCHEMBL11662569 | 0.88 | CACNA1C (0.44) | CACNA1CSCN5ADRD2HTR2AHTR2B | |
| SCHEMBL11660421 | 0.88 | CACNA1C (0.44) | CACNA1CSCN5ADRD2HTR2AHTR2B | |
| SCHEMBL11053009 | 0.86 | DRD2 (0.50) | CACNA1CSCN5ADRD2HTR2AHTR2B | |
| SCHEMBL11663497 | 0.86 | PPARA (0.46) | CACNA1CSCN5APPARAALDH1A1 | |
| SCHEMBL11656116 | 0.86 | DRD2 (0.47) | CACNA1CSCN5ADRD2HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117165-A | ANTIULCER, HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-09-26 | — | — | US | disclosed |