Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662195 | 0.81 | SLC6A2 (0.44) | SLC6A2TAAR1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL11665405 | 0.81 | HPGD (0.37) | TAAR1CYP2C9CYP2C19LMNACYP2D6 | |
| SCHEMBL11855768 | 0.80 | SLC6A2 (0.47) | SLC6A2TAAR1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL11659390 | 0.79 | HTR3E (0.44) | TAAR1CYP3A4RECQLTSHR | |
| SCHEMBL28374740 | 0.79 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6552343 | 0.79 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL11659440 | 0.77 | HTR2A (0.46) | TAAR1LMNAALDH1A1 | |
| SCHEMBL11444579 | 0.74 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3461269 | 0.74 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1698269 | 0.74 | SLC6A2 (0.67) | SLC6A2TAAR1CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4074051-A | DEVELOPING AGENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |