Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100367 | 0.84 | AKR1C2 (0.47) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL11661492 | 0.84 | SMN1; SMN2 (0.43) | BRD4MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL11663913 | 0.78 | METAP1 (0.42) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL11665240 | 0.77 | BRD4 (0.46) | BRD4PTPN11PLA2G4BMEN1KMT2A | |
| SCHEMBL9142278 | 0.76 | AKR1B1 (0.45) | ALDH1A1LMNA | |
| SCHEMBL4897451 | 0.75 | MEN1 (0.49) | BRD4MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1387817 | 0.75 | PPARG (0.49) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL11662750 | 0.75 | ABCB11 (0.38) | FFAR1KDM4E | |
| SCHEMBL11663442 | 0.75 | FFAR1 (0.40) | GAAMAPTL3MBTL1FFAR1FFAR4 | |
| SCHEMBL17853891 | 0.73 | METAP1 (0.46) | MEN1KMT2ANPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |