Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5156531 | 0.74 | OPRL1 (0.67) | OPRM1OPRL1OPRK1 | |
| Bicarbonate SCHEMBL5162054 | 0.73 | OPRL1 (0.64) | OPRM1OPRL1OPRK1 | |
| SCHEMBL2782210 | 0.69 | OPRL1 (0.78) | OPRM1OPRL1OPRK1 | |
| SCHEMBL27525174 | 0.68 | AKR1C1 (0.43) | AKR1C1OPRM1OPRL1HDAC4MEN1 | |
| SCHEMBL11500280 | 0.68 | MEN1 (0.43) | AKR1C1OPRM1OPRL1HDAC4MEN1 | |
| SCHEMBL28298245 | 0.66 | OPRM1 (0.48) | OPRM1OPRL1OPRK1 | |
| SCHEMBL11496520 | 0.66 | AKR1C1 (0.41) | AKR1C1OPRM1OPRL1HDAC4MEN1 | |
| SCHEMBL27886883 | 0.66 | AKR1C1 (0.41) | AKR1C1OPRM1OPRL1HDAC4MEN1 | |
| SCHEMBL19335064 | 0.65 | AKR1C1 (0.68) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL19335085 | 0.65 | AKR1C1 (0.68) | AKR1C1HDAC4MEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130576-A | Method for preparing isocyanates from halosilyl carbamates | UNION CARBIDE CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |
| US-4064151-A | ISOCYANATE INTERMEDIATES | UNITED CARBIDE CORPORATION (US) | 1977-12-20 | — | — | US | disclosed |