Ethylbenzene

Ethylbenzene

SCHEMBL11665409

CCc1ccccc1.CCc1ccccc1.OP(O)(O)=S.OP(O)(O)=S.[NaH]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.67
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 2/20 0.44
POLB P06746 1/20 0.44
ALDH1A1 P00352 1/20 0.41
TSHR P16473 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
CYP2C19 P33261 1/20 0.38
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
CETP P11597 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL5460199 0.98 TP53 (0.70) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL5552776 0.98 TP53 (0.70) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL27469318 0.95 TP53 (0.67) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL11465912 0.95 TP53 (0.67) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL7758164 0.95 TP53 (0.67) TP53SMN1; SMN2RAB9APOLBALDH1A1
SCHEMBL27335693 0.85 TAAR1 (0.52) TP53SMN1; SMN2ALDH1A1TSHRTAAR1
Ethylbenzene SCHEMBL9474534 0.84 TP53 (0.93) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL28009971 0.84 TP53 (0.93) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL216251 0.84 TP53 (0.93) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL28056495 0.84 TP53 (0.93) TP53SMN1; SMN2RAB9APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4099954-A Amide phosphorothiolate herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-07-11 US disclosed