Ethylbenzene

Ethylbenzene

SCHEMBL5552776

CCc1ccccc1.OP(O)(O)=S.OP(O)(O)=S

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.70
SMN1; SMN2 Q16637 3/20 0.46
RAB9A P51151 2/20 0.46
POLB P06746 1/20 0.46
ALDH1A1 P00352 1/20 0.43
TSHR P16473 2/20 0.42
TAAR1 Q96RJ0 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP2C19 P33261 1/20 0.39
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
CALM1 P0DP23 1/20 0.39
CETP P11597 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL5460199 1.00 TP53 (0.70) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL27469318 0.98 TP53 (0.67) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL11465912 0.98 TP53 (0.67) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL7758164 0.98 TP53 (0.67) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL11665409 0.98 TP53 (0.67) TP53SMN1; SMN2RAB9APOLBALDH1A1
SCHEMBL27335693 0.87 TAAR1 (0.52) TP53SMN1; SMN2ALDH1A1TSHRTAAR1
Ethylbenzene SCHEMBL9474534 0.87 TP53 (0.93) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL28009971 0.87 TP53 (0.93) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL216251 0.87 TP53 (0.93) TP53SMN1; SMN2RAB9APOLBALDH1A1
Ethylbenzene SCHEMBL28056495 0.87 TP53 (0.93) TP53SMN1; SMN2RAB9APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10145417-B2 Grease composition-filled ball bearing, pivot assembly bearing including the ball bearing, and hard disk drive including the pivot assembly bearing MINEBEA MITSUMI INC. (JP) 2018-12-04 US disclosed
US-20180003233-A1 GREASE COMPOSITION-FILLED BALL BEARING, PIVOT ASSEMBLY BEARING INCLUDING THE BALL BEARING, AND HARD DISK DRIVE INCLUDING THE PIVOT ASSEMBLY BEARING MINEBEA MITSUMI INC. (JP) 2018-01-04 US disclosed
EP-1840399-B1 COLLAPSIBLE COLUMN NSK LTD (JP) 2014-06-18 EP disclosed
EP-1840399-A1 COLLAPSIBLE COLUMN NSK Ltd., (JP) 2007-10-03 EP disclosed
US-7067463-B2 Pivot assembly bearing MINEBEA CO., LTD. (JP) 2006-06-27 US disclosed
US-20030220207-A1 Vibration resistant bearing MINEBEA MITSUMI INC. (JP) 2003-11-27 US disclosed
US-20030158052-A1 Pivot assembly bearing MINEBEA MITSUMI INC. (JP) 2003-08-21 US disclosed
US-6482779-B2 SYNTHETIC OIL AS A BASE OIL, LITHIUM SOAP THICKENER, ADDITIVE SELECTED FROM ORGANIC MOLYBDENUM COMPOUND, ORGANIC FATTY ACID COMPOUND OR A DERIVATIVE THEREOF, ORGANIC PHOSPHORUS COMPOUND NSK LTD. (JP) 2002-11-19 US disclosed
US-20020002119-A1 Lubricating grease composition and rolling apparatus comprising same NSK LTD. (JP) 2002-01-03 US disclosed
EP-1136545-A2 Lubricating grease composition and rolling apparatus comprising same NSK LTD (JP) 2001-09-26 EP disclosed
US-5252391-A Surface treated sliding or rolling contact element and rolling bearing NIPPON SEIKO KABUSHIKI KAISHA (JP) 1993-10-12 US disclosed