Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 7/20 | 0.54 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 6/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302086 | 0.87 | GNAI3 (0.53) | GNAI3GNAO1GNAI1EPHX1PRCP | |
| SCHEMBL7041937 | 0.85 | GNAI3 (0.56) | GNAI3GNAO1GNAI1EPHX1PRCP | |
| SCHEMBL7042804 | 0.85 | GNAI3 (0.56) | GNAI3GNAO1GNAI1EPHX1PRCP | |
| SCHEMBL10906234 | 0.78 | PRCP (0.49) | GNAI3GNAO1GNAI1PRCPGBA1 | |
| SCHEMBL6401701 | 0.76 | GNAI3 (0.51) | GNAI3GNAO1GNAI1PRCPGBA1 | |
| SCHEMBL10945126 | 0.76 | GNAI3 (0.51) | GNAI3GNAO1GNAI1PRCPGBA1 | |
| SCHEMBL3265058 | 0.73 | GNAI3 (0.92) | GNAI3GNAO1GNAI1EPHX1PRCP | |
| SCHEMBL7043466 | 0.72 | GNAI3 (0.50) | GNAI3GNAO1GNAI1EPHX1PRCP | |
| SCHEMBL19604164 | 0.72 | GNAI3 (0.96) | GNAI3GNAO1GNAI1EPHX1PRCP | |
| SCHEMBL7319928 | 0.72 | GNAI3 (0.96) | GNAI3GNAO1GNAI1EPHX1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004608-A1 | 4-Acylamido-hexahydropyrimidines, and process for their preparation | BASF Aktiengesellschaft (DE) | 1979-10-17 | — | — | EP | claimed |
| EP-0004608-A1 | 4-Acylamido-hexahydropyrimidines, and process for their preparation | BASF Aktiengesellschaft (DE) | 1979-10-17 | — | — | EP | disclosed |
| EP-0004608-A1 | 4-Acylamido-hexahydropyrimidines, and process for their preparation | BASF Aktiengesellschaft (DE) | 1979-10-17 | — | — | EP | disclosed |