SCHEMBL11667283

SCHEMBL11667283

C=CCOC(=O)[C@H](N)CCCCN

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.50
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
DPP7 Q9UHL4 10/20 0.36
DPP8 Q6V1X1 5/20 0.36
DPP9 Q86TI2 5/20 0.36
DPP4 P27487 2/20 0.36
RNPEP Q9H4A4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CPB2 Q96IY4 1/20 0.36
TSHR P16473 1/20 0.35
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
FAP Q12884 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL369325 1.00 GSR (0.50) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL369324 1.00 GSR (0.50) GSRGNAI3GNAO1GNAI1DPP7
Hydrochloric Acid SCHEMBL11554720 0.98 GSR (0.48) GSRGNAI3GNAO1GNAI1DPP7
Hydrochloric Acid SCHEMBL11554718 0.98 GSR (0.48) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL5203658 0.95 GSR (0.42) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL5203652 0.95 GSR (0.42) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL5203643 0.95 GSR (0.42) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL722132 0.92 GSR (0.43) GSRGNAI3GNAO1GNAI1DPP7
SCHEMBL7950462 0.87 TDP1 (0.39) GSRDPP7TDP1TSHRMAPT
SCHEMBL15388600 0.87 GSR (0.44) GSRGNAI3GNAO1GNAI1DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4108723-A USING BACTERIA PRODUCED PROTEASE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-08-22 US disclosed