Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203658 | 0.89 | GSR (0.42) | TDP1MAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL5203652 | 0.89 | GSR (0.42) | TDP1MAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL5203643 | 0.89 | GSR (0.42) | TDP1MAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL369325 | 0.87 | GSR (0.50) | TDP1MAPTCACNA1BAPBA1TSHR | |
| SCHEMBL11667283 | 0.87 | GSR (0.50) | TDP1MAPTCACNA1BAPBA1TSHR | |
| SCHEMBL369324 | 0.87 | GSR (0.50) | TDP1MAPTCACNA1BAPBA1TSHR | |
| Hydrochloric Acid SCHEMBL11554720 | 0.85 | GSR (0.48) | TDP1MAPTCACNA1BAPBA1TSHR | |
| Hydrochloric Acid SCHEMBL11554718 | 0.85 | GSR (0.48) | TDP1MAPTCACNA1BAPBA1TSHR | |
| SCHEMBL5341469 | 0.83 | MAPT (0.40) | TDP1MAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL3808776 | 0.82 | TDP1 (0.38) | TDP1MAPTCACNA1BAPBA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271198-B1 | CYCLIC PEPTIDES | GENENTECH, INC. | 2001-08-07 | — | — | US | disclosed |