Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18677661 | 0.91 | ALDH1A1 (0.68) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL14543272 | 0.87 | ALDH1A1 (0.73) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL8059098 | 0.86 | ALDH1A1 (0.78) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL6037493 | 0.84 | ALDH1A1 (0.75) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL12655119 | 0.84 | KMT2A (0.78) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL11668327 | 0.83 | ALDH1A1 (0.63) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL3984703 | 0.83 | ALDH1A1 (0.63) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| Phenyl Phenylcarbamate SCHEMBL272994 | 0.81 | ALDH1A1 (0.76) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL6037499 | 0.81 | ALDH1A1 (0.75) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| Phenyl M-Tolylcarbamate SCHEMBL29739712 | 0.80 | ALDH1A1 (0.78) | ALDH1A1GAAHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018744-A | Storage stable polyester-polyurethane-producing compositions | ATLANTIC RICHFIELD COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-3950285-A | PREPARATION OF POLYMERIC URETHANES FROM DICARBAMATES | ATLANTIC RICHFIELD COMPANY (US) | 1976-04-13 | — | — | US | disclosed |