Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670664 | 0.91 | ALDH1A1 (0.40) | TSHRL3MBTL1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11670644 | 0.89 | FABP7 (0.39) | TSHRSMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL11672284 | 0.89 | TP53 (0.39) | TSHRTDP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11671783 | 0.84 | KMT2A (0.43) | TSHRL3MBTL1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11670393 | 0.83 | KMT2A (0.43) | TSHRSMN1; SMN2MAPTHTTGAA | |
| SCHEMBL11675539 | 0.83 | TSHR (0.43) | TSHRL3MBTL1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11671695 | 0.81 | KMT2A (0.43) | TSHRALDH1A1MAPTNPC1GAA | |
| SCHEMBL11671552 | 0.81 | MEN1 (0.35) | TSHRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11670591 | 0.81 | TDP1 (0.37) | TSHRL3MBTL1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11670540 | 0.80 | TDP1 (0.40) | TSHRL3MBTL1TDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039526-A | PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4039539-A | 1,2,4-Triazole-azo-aniline cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |