Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | FPR3 | P25089 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054490 | 0.85 | ADRB2 (0.60) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL11670036 | 0.84 | ADRB3 (0.52) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL13090612 | 0.80 | ADRB2 (0.52) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL1008173 | 0.78 | ADRB2 (0.55) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL1008171 | 0.78 | ADRB2 (0.55) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL1008170 | 0.78 | ADRB2 (0.55) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL2012566 | 0.77 | ADRB2 (0.61) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL2012563 | 0.77 | ADRB2 (0.61) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL2012565 | 0.77 | ADRB2 (0.61) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL11670459 | 0.77 | MEN1 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024281-A | N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |