Histidine

Histidine

SCHEMBL11670599

N[C@@H](Cc1c[nH]cn1)C(=O)O.O=P(O)(O)F.O=P(O)(O)F

nearest known ligand 0.41

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP1A2 P05177 1/20 0.40
PTPN1 P18031 1/20 0.40
PTPRC P08575 1/20 0.38
ALPI P09923 1/20 0.37
PKM P14618 1/20 0.37
PTGS1 P23219 1/20 0.37
XIAP P98170 1/20 0.37
GRIA1 P42261 1/20 0.35
GRIA2 P42262 1/20 0.35
GRIA3 P42263 1/20 0.35
GRIA4 P48058 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Histidine SCHEMBL11670595 1.00 SLC7A5 (0.41) SLC7A5CYP3A4CYP1A2PTPN1PTPRC
Histidine SCHEMBL11671364 1.00 SLC7A5 (0.41) SLC7A5CYP3A4CYP1A2PTPN1PTPRC
Histidine SCHEMBL11670312 1.00 SLC7A5 (0.41) SLC7A5CYP3A4CYP1A2PTPN1PTPRC
Histidine SCHEMBL11670811 0.99 SLC7A5 (0.40) SLC7A5CYP3A4CYP1A2PTPN1PTPRC
Histidine SCHEMBL11670808 0.99 SLC7A5 (0.40) SLC7A5CYP3A4CYP1A2PTPN1PTPRC
Histidine SCHEMBL11671296 0.99 SLC7A5 (0.40) SLC7A5CYP3A4CYP1A2PTPN1PTPRC
Histidine SCHEMBL11671298 0.99 SLC7A5 (0.40) SLC7A5CYP3A4CYP1A2PTPN1PTPRC
Histidine SCHEMBL15670767 0.94 SLC7A5 (0.43) SLC7A5CYP3A4CYP1A2PTPN1PTPRC
Histidine SCHEMBL28923637 0.94 SLC7A5 (0.43) SLC7A5CYP3A4CYP1A2PTPN1PTPRC
Histidine SCHEMBL503658 0.94 SLC7A5 (0.43) SLC7A5CYP3A4CYP1A2PTPN1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4064138-A Amino acid derivatives GENERAL MILLS, INC. (US) 1977-12-20 US claimed