Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671562 | 0.87 | CYP1A2 (0.60) | KDM4EDNM1CHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL19396668 | 0.82 | KDM4E (0.71) | KDM4EDNM1CHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5506201 | 0.80 | KDM4E (0.47) | KDM4EDNM1CHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31721107 | 0.79 | KDM4E (0.67) | KDM4EDNM1CHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL1883794 | 0.79 | KDM4E (0.67) | KDM4EDNM1CHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7160696 | 0.77 | BCHE (0.51) | KDM4EDNM1ALDH1A1CYP1A2 | |
| SCHEMBL7689676 | 0.77 | BCHE (0.51) | KDM4EDNM1ALDH1A1CYP1A2 | |
| SCHEMBL20024581 | 0.76 | KDM4E (0.63) | KDM4EDNM1CHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL28860787 | 0.76 | KDM4E (0.63) | KDM4EDNM1CHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13939066 | 0.76 | KDM4E (0.63) | KDM4EDNM1CHRM2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021539-A | Skin treating cosmetic compositions containing N-polyhydroxyalkyl-amines | HENKEL & CIE G.M.B.H. (DT) | 1977-05-03 | — | — | US | disclosed |