SCHEMBL5506201

SCHEMBL5506201

N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO.c1ccc(CNCc2ccccn2)nc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ CHRM2 P08172 1/20 0.42
▸ DNM1 Q05193 1/20 0.41
▸ MAOA P21397 2/20 0.40
▸ MAOB P27338 2/20 0.40
▸ ALDH1A1 P00352 4/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ POLB P06746 2/20 0.39
▸ PRMT1 Q99873 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ PTPRA P18433 1/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ LMNA P02545 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11670929 0.80 KDM4E (0.61) KDM4ESMN1; SMN2CHRM2DNM1MAOA
Hydrochloric Acid SCHEMBL18115133 0.74 LMNA (0.48) KDM4EL3MBTL1LMNA
Hydrochloric Acid SCHEMBL4112448 0.74 LMNA (0.48) KDM4EL3MBTL1LMNA
Hydrochloric Acid SCHEMBL2253326 0.74 LMNA (0.48) KDM4EL3MBTL1LMNA
Hydrochloric Acid SCHEMBL1199353 0.74 LMNA (0.48) KDM4EL3MBTL1LMNA
SCHEMBL28730 0.74 LMNA (0.52) KDM4EL3MBTL1LMNA
SCHEMBL2560773 0.74 LMNA (0.52) KDM4EL3MBTL1LMNA
SCHEMBL5706423 0.74 LMNA (0.52) KDM4EL3MBTL1LMNA
SCHEMBL3114813 0.74 LMNA (0.52) KDM4EL3MBTL1LMNA
SCHEMBL22963142 0.74 LMNA (0.52) KDM4EL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1797106-A1 SYNTHESIS OF RADIOLABELED SUGAR METAL COMPLEXES Triumf, operating as a joint venture by the Governors of the Universities of Alberta, (CA) 2007-06-20 — — EP disclosed
WO-2006026855-A1 SYNTHESIS OF RADIOLABELED SUGAR METAL COMPLEXES TRIUMF, OPERATING AS A JOINT VENTURE BY THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, THE UNIVERSITY OF BRITISH COLUMBIA, CARLETON (CA) 2006-03-16 — — WO disclosed
US-20060051291-A1 Synthesis of radiolabeled sugar metal complexes ADVANCED APPLIED PHYSICS SOLUTIONS, INC. (CA) 2006-03-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060051291-A1 Synthesis of radiolabeled sugar metal complexes GFPT1, CSGALNACT1, TST KDM4E 3069/4885SMN1; SMN2 4678/4885CHRM2 2781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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