Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672551 | 1.00 | ALDH1A1 (0.62) | ALDH1A1HSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL11878417 | 0.89 | ALDH1A1 (0.61) | ALDH1A1HSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL11878408 | 0.89 | ALDH1A1 (0.61) | ALDH1A1HSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL11577111 | 0.89 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL11577116 | 0.89 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL11868361 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL11868358 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL11700631 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL11700638 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EMAPTKMT2A | |
| SCHEMBL3951922 | 0.87 | MAPK1 (0.59) | ALDH1A1HSD17B10KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065621-A | Process for 3-alkyl and 3-phenyl cephalosporins | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4013651-A | 3-SUBSTITUTED AMINO-CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |