SCHEMBL11673003

SCHEMBL11673003

CCCc1ccccn1.c1ccc(-c2ccccn2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.53
CYP2C19 P33261 2/20 0.53
CYP2D6 P10635 1/20 0.53
CYP19A1 P11511 1/20 0.53
CYP2C9 P11712 1/20 0.53
SREBF2 Q12772 1/20 0.50
HRH3 Q9Y5N1 1/20 0.47
HRH1 P35367 2/20 0.47
LMNA P02545 2/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ALOX15 P16050 1/20 0.46
HIF1A Q16665 2/20 0.46
CTSK P43235 1/20 0.45
KDM4E B2RXH2 2/20 0.44
CYP2A6 P11509 1/20 0.44
HSP90AA1 P07900 1/20 0.44
MAPT P10636 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ASIC3 Q9UHC3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL9115752 0.89 KDM4E (0.56) CYP1A2CYP2C19CYP2D6CYP19A1CYP2C9
SCHEMBL29583126 0.85
SCHEMBL10527 0.85
SCHEMBL123540 0.83 HRH1 (0.55) CYP1A2CYP2C19CYP2D6CYP19A1CYP2C9
SCHEMBL30101413 0.83 HRH1 (0.59) CYP1A2CYP2C19CYP2D6HRH3HRH1
Hydrochloric Acid SCHEMBL28050227 0.83 ALDH1A1 (0.62) CYP1A2CYP2C19CYP2D6HRH3HRH1
Bromide SCHEMBL14801933 0.83 HRH1 (0.59) CYP1A2CYP2C19CYP2D6HRH3HRH1
SCHEMBL11564094 0.83 HRH1 (0.59) CYP1A2CYP2C19CYP2D6HRH3HRH1
Iodide SCHEMBL22551708 0.83 HRH1 (0.59) CYP1A2CYP2C19CYP2D6HRH3HRH1
Ammonia Solution, Strong SCHEMBL1509120 0.83 HRH1 (0.59) CYP1A2CYP2C19CYP2D6HRH3HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4011392-A COATINGS THE SHERWIN-WILLIAMS COMPANY (US) 1977-03-08 US disclosed