SCHEMBL11673103

SCHEMBL11673103

CC1CCC[C@]2(C)CC[C@H](O)C[C@H]12

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR1I3 Q14994 1/20 0.50
AKR1B10 O60218 1/20 0.40
SHBG P04278 3/20 0.37
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
LMNA P02545 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11672190 1.00 NR1I3 (0.50) NR1I3AKR1B10SHBGCDK5CDK5R1
SCHEMBL11671836 1.00 NR1I3 (0.50) NR1I3AKR1B10SHBGCDK5CDK5R1
SCHEMBL11672814 1.00 NR1I3 (0.50) NR1I3AKR1B10SHBGCDK5CDK5R1
SCHEMBL11671840 1.00 NR1I3 (0.50) NR1I3AKR1B10SHBGCDK5CDK5R1
SCHEMBL1247588 0.76 NR1I3 (0.38) NR1I3AKR1B10CDK5CDK5R1
SCHEMBL4498548 0.76 NR1I3 (0.64) NR1I3AKR1B10SHBGCDK5CDK5R1
SCHEMBL4498540 0.76 NR1I3 (0.64) NR1I3AKR1B10SHBGCDK5CDK5R1
Dihydroeudesmol SCHEMBL24043780 0.75 TRPA1 (0.50) NR1I3CDK5CDK5R1
SCHEMBL21886380 0.75 SMN1; SMN2 (0.36) NR1I3
SCHEMBL21832008 0.75 SMN1; SMN2 (0.36) NR1I3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4008184-A 6,10 Dimethyl bicyclo(4,4,0)decane or decene alcohol and ester perfume compositions FIRMENICH S.A. (CH) 1977-02-15 US disclosed