Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974601 | 0.97 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL11795941 | 0.92 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL11094954 | 0.89 | KCNH2 (0.66) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6944690 | 0.89 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL8628519 | 0.89 | KCNH2 (0.66) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL1449327 | 0.89 | HDAC3 (0.58) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL8086700 | 0.89 | KCNH2 (0.66) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL8708196 | 0.89 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL11097968 | 0.89 | KCNH2 (0.66) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL7167397 | 0.89 | KCNH2 (0.66) | HDAC3HDAC1HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4020232-A | COATINGS OF AN AMINE DERIVATIVE AND A LEUCO DYE CAPABLE OF REACTING WITH SAID AMINE | MITSUBISHI PAPER MILLS, LTD. (JA) | 1977-04-26 | — | — | US | disclosed |
| US-3984605-A | Heat sensitive recording material containing decolorizing agent | MITSUBISHI PAPER MILLS, LTD. (JA) | 1976-10-05 | — | — | US | disclosed |