Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628519 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11816138 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7231682 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8086700 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11097968 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15933358 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11094954 | 1.00 | KCNH2 (0.66) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL11818106 | 0.98 | KCNH2 (0.64) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL5907917 | 0.98 | KCNH2 (0.64) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| Bromide SCHEMBL28674611 | 0.98 | KCNH2 (0.64) | KCNH2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383089-B1 | Cold curing reactive resin blend and its use | BAYER AG (DE) | 1994-04-06 | — | — | EP | claimed |
| US-5084544-A | Reaction of polyepoxides and polyisocyanates to form polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | claimed |
| US-4450114-A | Process for production of sulfuric acid semiesters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-22 | — | — | US | claimed |
| US-4351765-A | Process for the production of compounds having in the molecule at least one β-sulfatoethyl-sulfone group and at least one sulfonic acid group | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-09-28 | — | — | US | claimed |
| US-4224416-A | Degradable plastic composition containing amine | OWENS-ILLINOIS, INC. (US) | 1980-09-23 | — | — | US | claimed |
| US-3966594-A | SOLVENT EXTRACTION WITH TERTIERY AMINE AND ALKALI | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-06-29 | — | — | US | claimed |
| CN-101687655-A | Organized clay complex, method for producing the same, and resin complex containing organized clay complex | SHOWA DENKO KK | 2010-03-31 | — | — | CN | disclosed |
| CN-1253498-C | Polyolefin resin composition | SEKISUI CHEMICAL CO LTD (JP) | 2006-04-26 | — | — | CN | disclosed |
| CN-1154687-C | Rubber composition and preumatic tire | ������������ʽ���� | 2004-06-23 | — | — | CN | disclosed |
| US-6630434-B2 | A low viscosity aqueous cleaner diluted to high viscosity to cling to vertical walls; rod micelle thickener of an amine oxide or quaternary ammonium compound, a glycol monoether; alkalinity; sequestering; baked on foods; low temperature | ECOLAB INC. | 2003-10-07 | — | — | US | disclosed |
| EP-0846724-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2003-08-20 | — | — | EP | disclosed |
| EP-0857752-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE MADE BY USING THE SAME | BRIDGESTONE CORP (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6559209-B1 | Method of making a rubber composition which is improved in a dispersibility of silica into rubber, a heat generating property and an abrasion property. The rubber composition comprises 15 to 85 parts by weight of silica per 100 parts of | BRIDGESTONE CORPORATION (JP) | 2003-05-06 | — | — | US | disclosed |
| US-4853146-A | Thickening compositions and thickened aqueous acid solutions | AKZO N.V. (NL) | 1989-08-01 | — | — | US | disclosed |
| EP-0276501-A2 | Thickening compositions and thickened aqueous acid solutions | Akzo Nobel N.V. (NL) | 1988-08-03 | — | — | EP | disclosed |
| US-4450114-A | Process for production of sulfuric acid semiesters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-22 | — | — | US | disclosed |
| US-4351765-A | Process for the production of compounds having in the molecule at least one β-sulfatoethyl-sulfone group and at least one sulfonic acid group | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-09-28 | — | — | US | disclosed |
| US-4224416-A | Degradable plastic composition containing amine | OWENS-ILLINOIS, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4020232-A | COATINGS OF AN AMINE DERIVATIVE AND A LEUCO DYE CAPABLE OF REACTING WITH SAID AMINE | MITSUBISHI PAPER MILLS, LTD. (JA) | 1977-04-26 | — | — | US | disclosed |
| US-3966594-A | SOLVENT EXTRACTION WITH TERTIERY AMINE AND ALKALI | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-06-29 | — | — | US | disclosed |