SCHEMBL11673255

SCHEMBL11673255

COC(=O)C=Cc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
TYR P14679 1/20 0.60
CA7 P43166 1/20 0.60
CA9 Q16790 1/20 0.60
CA14 Q9ULX7 1/20 0.60
PTPN1 P18031 1/20 0.53
TRPM8 Q7Z2W7 6/20 0.52
NR1H4 Q96RI1 3/20 0.52
TTR P02766 1/20 0.51
APP P05067 1/20 0.51
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KMT2A Q03164 2/20 0.50
EPHX2 P34913 1/20 0.48
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
JAK2 O60674 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2602540 0.93 CA12 (0.68) CA12CA1CA2TYRCA7
SCHEMBL2602501 0.92 CA12 (0.55) CA12CA1CA2TYRCA7
SCHEMBL2602502 0.92 CA12 (0.55) CA12CA1CA2TYRCA7
SCHEMBL2602587 0.89 CA12 (0.62) CA12CA1CA2TYRCA7
SCHEMBL11672941 0.87 TRPM8 (0.50) CA12CA7CA9CA14TRPM8
SCHEMBL11672938 0.87 TRPM8 (0.50) CA12CA7CA9CA14TRPM8
SCHEMBL11672946 0.85 TRPM8 (0.53) CA12CA7CA9CA14TRPM8
SCHEMBL13899903 0.84 CA12 (0.70) CA12CA1CA2TYRCA7
SCHEMBL11673887 0.84 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL18011709 0.84 CA12 (0.65) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4018606-A Organic azo pigment sensitizers for photoconductive layers EASTMAN KODAK COMPANY (US) 1977-04-19 US disclosed
US-4018607-A Crystalline organic pigment sensitizers for photoconductive layers EASTMAN KODAK COMPANY (US) 1977-04-19 US disclosed