Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.73 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673368 | 1.00 | PLCG1 (0.79) | PLCG1TDP1CTDSP1MAPTNR1I2 | |
| SCHEMBL11648862 | 0.93 | PLCG1 (0.81) | PLCG1TDP1CTDSP1MAPTNR1I2 | |
| SCHEMBL11648858 | 0.93 | PLCG1 (0.81) | PLCG1TDP1CTDSP1MAPTNR1I2 | |
| SCHEMBL11038661 | 0.93 | TDP1 (0.84) | PLCG1TDP1CTDSP1MAPTNR1I2 | |
| SCHEMBL11038658 | 0.93 | TDP1 (0.84) | PLCG1TDP1CTDSP1MAPTNR1I2 | |
| SCHEMBL11042191 | 0.92 | PLCG1 (0.77) | PLCG1TDP1CTDSP1MAPTNR1I2 | |
| SCHEMBL11042193 | 0.92 | PLCG1 (0.77) | PLCG1TDP1CTDSP1MAPTNR1I2 | |
| SCHEMBL9623844 | 0.91 | PLCG1 (0.80) | PLCG1TDP1CTDSP1MAPTNR1I2 | |
| SCHEMBL9623847 | 0.91 | PLCG1 (0.80) | PLCG1TDP1CTDSP1MAPTNR1I2 | |
| SCHEMBL11038344 | 0.91 | PLCG1 (0.66) | PLCG1TDP1CTDSP1MAPTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044002-A | ACYL BROMIDES AND A BROMINE SCAVENGER | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |