Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042193 | 1.00 | PLCG1 (0.77) | PLCG1TDP1CTDSP1ALDH1A1L3MBTL1 | |
| SCHEMBL11673368 | 0.92 | PLCG1 (0.79) | PLCG1TDP1CTDSP1ALDH1A1L3MBTL1 | |
| SCHEMBL11673364 | 0.92 | PLCG1 (0.79) | PLCG1TDP1CTDSP1ALDH1A1L3MBTL1 | |
| SCHEMBL11648862 | 0.91 | PLCG1 (0.81) | PLCG1TDP1CTDSP1ALDH1A1L3MBTL1 | |
| SCHEMBL11648858 | 0.91 | PLCG1 (0.81) | PLCG1TDP1CTDSP1ALDH1A1L3MBTL1 | |
| SCHEMBL9623844 | 0.91 | PLCG1 (0.80) | PLCG1TDP1CTDSP1ALDH1A1L3MBTL1 | |
| SCHEMBL9623847 | 0.91 | PLCG1 (0.80) | PLCG1TDP1CTDSP1ALDH1A1L3MBTL1 | |
| SCHEMBL11040053 | 0.90 | PLCG1 (0.79) | PLCG1TDP1CTDSP1ALDH1A1L3MBTL1 | |
| SCHEMBL11040054 | 0.90 | PLCG1 (0.79) | PLCG1TDP1CTDSP1ALDH1A1L3MBTL1 | |
| SCHEMBL11672827 | 0.89 | PLCG1 (0.61) | PLCG1TDP1CTDSP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034924-B1 | PROCESS FOR PREPARING 3-IODOMETHYL CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | disclosed |
| EP-0034924-A2 | Process for preparing 3-iodomethyl cephalosporins | ELI LILLY AND COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4266049-A | Process for 3-iodomethyl cephalosporins | ELI LILLY AND COMPANY (US) | 1981-05-05 | — | — | US | disclosed |