Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10528752 | 0.98 | GAA (0.51) | GAASMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL8031605 | 0.86 | ELANE (0.53) | GAASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL6026706 | 0.86 | ELANE (0.53) | GAASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL655368 | 0.86 | ELANE (0.53) | GAASMN1; SMN2LMNAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1171032 | 0.85 | ELANE (0.52) | GAASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL19707799 | 0.84 | KMT2A (0.48) | GAASMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL28986475 | 0.82 | ELANE (0.38) | GAASMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL28841753 | 0.81 | CHRM1 (0.55) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4681333 | 0.80 | KMT2A (0.52) | GAASMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL29033348 | 0.80 | TDP1 (0.50) | GAASMN1; SMN2HPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060544-A | COUPLERS | GAF CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4039524-A | Keto-amido containing phenylazo benzothiazole dyestuffs | GAF CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |
| US-3931145-A | POLYESTER | GAF CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |