Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031605 | 1.00 | ELANE (0.53) | ELANEGAAMMP8PIN1MEN1 | |
| SCHEMBL6026706 | 1.00 | ELANE (0.53) | ELANEGAAMMP8PIN1MEN1 | |
| Hydrochloric Acid SCHEMBL1171032 | 0.98 | ELANE (0.52) | ELANEGAAMMP8PIN1MEN1 | |
| SCHEMBL5954163 | 0.88 | ELANE (0.47) | ELANEMMP8CA12CA1CA2 | |
| SCHEMBL5954162 | 0.88 | ELANE (0.47) | ELANEMMP8CA12CA1CA2 | |
| SCHEMBL11675151 | 0.86 | GAA (0.53) | ELANEGAAMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL27296354 | 0.86 | ELANE (0.46) | ELANEMMP8PIN1CA12CA1 | |
| Hydrochloric Acid SCHEMBL10528752 | 0.85 | GAA (0.51) | ELANEGAAMEN1KMT2AMAPT | |
| SCHEMBL27631537 | 0.84 | GAA (0.54) | GAAMMP8PIN1MEN1NPC1 | |
| SCHEMBL2960871 | 0.84 | CA12 (0.62) | GAAMMP8PIN1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342599-B1 | HEAT-SENSITIVE RECORDING MATERIAL | SANKO CO LTD (JP) | 2021-06-16 | — | — | EP | disclosed |
| US-11007193-B2 | 2,4-pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2021-05-18 | — | — | US | disclosed |
| US-10828301-B2 | 2,4-pyrimidinediamine compounds and their uses | Rigel Pharmceuticals, Inc. (US) | 2020-11-10 | — | — | US | disclosed |
| US-10709703-B2 | 2,4-pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2020-07-14 | — | — | US | disclosed |
| US-10682350-B2 | 2,4-pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| US-20200085820-A1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2020-03-19 | — | — | US | disclosed |
| US-20190255047-A1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2019-08-22 | — | — | US | disclosed |
| US-10369148-B2 | 2,4-pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-10314840-B2 | 2,4-pyrimidinediamine compounds and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-10086634-B2 | Heat-sensitive recording material | SANKO CO., LTD. (JP) | 2018-10-02 | — | — | US | disclosed |
| WO-2000056708-A1 | CATALYTIC ASYMMETRIC SYNTHESIS OF CHIRAL AZIRIDINES | ARCH DEVELOPMENT CORPORATION (US) | 2000-09-28 | — | — | WO | disclosed |
| EP-0786690-B1 | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity | EASTMAN KODAK CO (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0942924-A2 | METHODS AND COMPOUNDS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |
| WO-1998022494-A2 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1998-05-28 | — | — | WO | disclosed |
| US-5747235-A | SILVER HALIDE ADSORBERS IN EMULSIONS FOR PHOTOGRAPHIC FILMS | EASTMAN KODAK COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| CN-1162761-A | Silver halide photographic emulsion layer with enhanced photosensitivity | EASTMAN KODAK CO (US) | 1997-10-22 | — | — | CN | disclosed |
| EP-0786690-A2 | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity | EASTMAN KODAK COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| US-4238506-A | SECONDARY OR TERTIARY AMIDE-SUBSTITUTED | BOEHRINGER MANNHEIM GMBH (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4113871-A | HYPOGLYCEMICALLY AND HYPOLIPIDEMICALLY ACTIVE DERIVATIVES OF PHENYL-ALKANE-CARBOXYLIC ACIDS | BOEHRINGER MANNHEIM GMBH (DE) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200085820-A1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | FCER2, FCGR1A, FCGR2A | ELANE 1928/4885GAA 2220/4885MMP8 1128/4885 |
| US-10086634-B2 | Heat-sensitive recording material | ASIC1, SCN1A, NPR1 | ELANE 3647/4885GAA 4231/4885MMP8 3077/4885 |
| US-10682350-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | ELANE 1928/4885GAA 2220/4885MMP8 1128/4885 |
| US-10709703-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | ELANE 1928/4885GAA 2220/4885MMP8 1128/4885 |
| US-10314840-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | ELANE 1928/4885GAA 2220/4885MMP8 1128/4885 |
| US-10369148-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | ELANE 1928/4885GAA 2220/4885MMP8 1128/4885 |
| US-11007193-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | ELANE 1928/4885GAA 2220/4885MMP8 1128/4885 |
| US-20190255047-A1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | FCER2, FCGR1A, FCGR2A | ELANE 1928/4885GAA 2220/4885MMP8 1128/4885 |
| US-10828301-B2 | 2,4-pyrimidinediamine compounds and their uses | FCER2, FCGR1A, FCGR2A | ELANE 1928/4885GAA 2220/4885MMP8 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.