Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22638695 | 0.85 | CA12 (0.51) | MAPTHPGDCA12CA9ALDH1A1 | |
| SCHEMBL11676039 | 0.83 | MAPT (0.73) | MAPTHPGDCA12CA9RAB9A | |
| SCHEMBL4883021 | 0.83 | CA12 (0.70) | MAPTHPGDCA12CA9RAB9A | |
| SCHEMBL6975706 | 0.80 | MAPT (0.51) | MAPTHPGDCA12CA9RAB9A | |
| SCHEMBL11676103 | 0.80 | MAPT (0.55) | MAPTHPGDCA12CA9RAB9A | |
| SCHEMBL11673814 | 0.80 | HPGD (0.53) | MAPTHPGDCA12CA9RAB9A | |
| SCHEMBL4624606 | 0.80 | HPGD (0.64) | MAPTHPGDCA12CA9RAB9A | |
| SCHEMBL11674749 | 0.79 | GSK3B (0.50) | HPGDLMNA | |
| SCHEMBL10778326 | 0.78 | MAPT (0.57) | MAPTHPGDCA12CA9RAB9A | |
| SCHEMBL11675640 | 0.78 | KMT2A (0.54) | MAPTHPGDCA12CA9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044151-A | Sulfamidophenethanolamine therapeutic process | MEAD JOHNSON & COMPANY (US) | 1977-08-23 | — | — | US | disclosed |