Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11674693 | 0.85 | KMT2A (0.40) | CES2CES1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28484796 | 0.83 | CES2 (0.50) | CES2CES1LMNAALDH1A1CYP1A2 | |
| SCHEMBL10949416 | 0.82 | NPSR1 (0.50) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11674132 | 0.81 | TSHR (0.60) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11254594 | 0.81 | CES2 (0.52) | CES2CES1LMNAALDH1A1CYP1A2 | |
| SCHEMBL11672970 | 0.80 | HPGD (0.54) | CYP3A4CYP2C9CYP2C19KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11834225 | 0.79 | CES2 (0.50) | CES2CES1LMNAALDH1A1CYP1A2 | |
| SCHEMBL11673208 | 0.79 | TPMT (0.45) | KMT2APOLBSMN1; SMN2PLAU | |
| Hydrochloric Acid SCHEMBL11843807 | 0.79 | HPGD (0.53) | CYP3A4CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL11848661 | 0.78 | ESR1 (0.59) | CES2CES1ALDH1A1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017540-A | INSECTICIDES, MITICIDES | THE UPJOHN COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3932661-A | Anthelmintic methods employing benzoyl chloride phenylhydrazones | THE UPJOHN COMPANY (US) | 1976-01-13 | — | — | US | disclosed |