Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11780293 | 0.98 | KCNH2 (0.47) | KCNH2BIRC5ALDH1A1TSHRATM | |
| SCHEMBL11678333 | 0.89 | KCNH2 (0.50) | KCNH2ALDH1A1TSHRATMNPSR1 | |
| SCHEMBL11678413 | 0.84 | ALDH1A1 (0.54) | KCNH2ALDH1A1TSHRATMNPSR1 | |
| SCHEMBL28167332 | 0.84 | ALDH1A1 (0.54) | KCNH2ALDH1A1TSHRATMNPSR1 | |
| SCHEMBL11832433 | 0.84 | KCNH2 (0.44) | KCNH2BIRC5CHRM2HTR1AADRA2A | |
| SCHEMBL11866467 | 0.84 | KCNH2 (0.44) | KCNH2BIRC5CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL11859118 | 0.82 | KCNH2 (0.43) | KCNH2BIRC5CHRM2HTR1AADRA2A | |
| SCHEMBL11786146 | 0.82 | ALDH1A1 (0.55) | KCNH2ALDH1A1TSHRATMNPSR1 | |
| SCHEMBL4900272 | 0.82 | HTR2A (0.55) | ALDH1A1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL30369240 | 0.82 | HTR2A (0.55) | ALDH1A1CHRM2ADRA2ACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | claimed |
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-3947593-A | ANTIVIRUL AGENTS | RICHARDSON-MERRELL INC. (US) | 1976-03-30 | — | — | US | disclosed |