Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678645 | 0.85 | CYP2C9 (0.38) | KDM4EMEN1MAPTKMT2APTPN1 | |
| SCHEMBL5665278 | 0.71 | KDM4E (0.44) | KDM4EMEN1MAPTKMT2AHSP90AA1 | |
| SCHEMBL28187924 | 0.68 | KDM4E (0.41) | KDM4EMEN1MAPTKMT2AHSP90AA1 | |
| SCHEMBL11653083 | 0.66 | KDM4E (0.49) | KDM4EMEN1MAPTKMT2AHSP90AA1 | |
| SCHEMBL1087151 | 0.66 | KDM4E (0.49) | KDM4EMEN1MAPTKMT2AHSP90AA1 | |
| SCHEMBL4314180 | 0.66 | PTPN1 (0.39) | PTPN1PTPRCPTPRFCDC25BMAOA | |
| SCHEMBL9787018 | 0.65 | KDM4E (0.45) | KDM4EMEN1MAPTKMT2AHSP90AA1 | |
| SCHEMBL18031579 | 0.65 | ING2 (0.46) | KDM4EMEN1MAPTKMT2AHSP90AA1 | |
| SCHEMBL11799540 | 0.65 | KMT2A (0.47) | KDM4EMEN1MAPTKMT2AHSP90AA1 | |
| SCHEMBL39261 | 0.65 | KMT2A (0.47) | KDM4EMEN1MAPTKMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006252-A | (3,5-DI-TERT-BUTYL-4-OXO-2,5-CYCLOHEXADIEN-1-YLIDENE)-(3,5-DI-TERT -BUTYL-4-HYDROXYPHENYL)METHANE | ETHYL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |