Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 9/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679942 | 0.98 | LPAR3 (0.47) | LPAR3LPAR2SOAT1NPC1RECQL | |
| SCHEMBL11678359 | 0.95 | NPC1 (0.43) | LPAR3LPAR2SOAT1NPC1RECQL | |
| SCHEMBL11679119 | 0.90 | NPC1 (0.35) | LPAR3LPAR2SOAT1NPC1RECQL | |
| SCHEMBL11677544 | 0.83 | HTT (0.41) | MEN1MAPTKMT2A | |
| SCHEMBL11680940 | 0.81 | CYP3A4 (0.40) | LPAR3LPAR2SOAT1NPC1RECQL | |
| SCHEMBL11680971 | 0.80 | SOAT1 (0.41) | LPAR3LPAR2SOAT1NPC1RECQL | |
| SCHEMBL11678348 | 0.79 | ACACB (0.40) | — | |
| SCHEMBL11679087 | 0.77 | NPC1 (0.43) | LPAR3LPAR2SOAT1NPC1RECQL | |
| SCHEMBL11676557 | 0.77 | USP2 (0.34) | LPAR3LPAR2NPC1RECQLRAB9A | |
| SCHEMBL4273729 | 0.76 | RAB9A (0.56) | SOAT1NPC1RECQLRAB9ANR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056617-A | Organic pyridazyl phosphorothioates and their use as insecticides | SANKYO COMPANY LIMITED (JA) | 1977-11-01 | — | — | US | claimed |
| US-4056617-A | Organic pyridazyl phosphorothioates and their use as insecticides | SANKYO COMPANY LIMITED (JA) | 1977-11-01 | — | — | US | disclosed |