SCHEMBL11679697

SCHEMBL11679697

O=C(ON=C1CCCCC1Cl)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.39
RAB9A P51151 3/20 0.38
ATM Q13315 1/20 0.38
LMNA P02545 1/20 0.38
NPC1 O15118 2/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
PKM P14618 1/20 0.36
ALDH1A1 P00352 2/20 0.36
POLB P06746 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
RBBP9 O75884 1/20 0.35
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CES2 O00748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11678900 0.95 LMNA (0.41) MIFRAB9AATMLMNANPC1
SCHEMBL11676880 0.80
SCHEMBL11676432 0.79
SCHEMBL11678502 0.79
SCHEMBL11677395 0.78
SCHEMBL11679759 0.78
SCHEMBL11678449 0.77 MEN1 (0.30) KMT2AMEN1
SCHEMBL11679064 0.77
SCHEMBL11680369 0.76
SCHEMBL11676222 0.76 MIF (0.30) MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4059625-A Certain oxime compositions and their use in controlling fungi STAUFFER CHEMICAL COMPANY (US) 1977-11-22 US disclosed
US-4007227-A Certain oxime compositions and their use in controlling fungi STAUFFER CHEMICAL COMPANY (US) 1977-02-08 US disclosed