Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678563 | 0.86 | PDE4D (0.55) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL4118586 | 0.83 | HTT (0.53) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL4128743 | 0.82 | PDE4B (0.51) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL4133074 | 0.82 | PDE4D (0.51) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL6717832 | 0.81 | PDE4D (0.56) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL27860093 | 0.81 | PDE4D (0.56) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL7198258 | 0.81 | PDE4D (0.50) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL4255074 | 0.81 | PDE4D (0.53) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL4120097 | 0.81 | PDE4D (0.50) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL4126956 | 0.81 | PDE4D (0.50) | PDE4DMAPTTDP1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4028348-A | 6-Amino-5β,19-cycloandrostane derivatives | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1977-06-07 | — | — | US | disclosed |