Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HMGCR | P04035 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27982790 | 0.86 | MAPT (0.67) | PDE4DMAPTTDP1HMGCRLMNA | |
| SCHEMBL23302233 | 0.86 | HTT (0.58) | PDE4DMAPTTDP1HMGCRLMNA | |
| SCHEMBL27860093 | 0.85 | PDE4D (0.56) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL514174 | 0.84 | MAPT (0.47) | PDE4DMAPTTDP1HMGCRLMNA | |
| SCHEMBL27848363 | 0.84 | MAPT (0.47) | PDE4DMAPTTDP1HMGCRLMNA | |
| SCHEMBL24069248 | 0.84 | PDE4D (0.49) | PDE4DMAPTTDP1HMGCRLMNA | |
| SCHEMBL28193844 | 0.84 | HMGCR (0.47) | PDE4DMAPTTDP1HMGCRLMNA | |
| SCHEMBL4608592 | 0.84 | PDE4D (0.55) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL8544960 | 0.84 | PDE4D (0.58) | PDE4DMAPTTDP1LMNAMAPK1 | |
| SCHEMBL11678563 | 0.84 | PDE4D (0.55) | PDE4DMAPTTDP1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101891604-A | Method for synthesizing 2,4,5-trimethoxyethylphenylketone intermediate of alpha-asarin | GUANGXI TRADITIONAL CHINESE MEDICAL UNIVERSITY | 2010-11-24 | — | — | CN | claimed |
| CN-101195562-A | Novel method for synthesizing alpha-asarone | GUANGXI TRADITIONAL CHINESE ME (CN) | 2008-06-11 | — | — | CN | claimed |
| CN-110128248-A | It is a kind of green simplicity prepare alpha-ararin technique | 承德石油高等专科学校 | 2019-08-16 | — | — | CN | disclosed |
| CN-109651199-A | A kind of histon deacetylase (HDAC) and the double target spot inhibitor of micro-pipe and preparation method thereof | 青岛大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-102199077-B | Method for producing (E)-2,4,5-trimethoxy-1-propenylbenzene | LU CHAO | 2013-01-23 | — | — | CN | disclosed |
| CN-101891604-A | Method for synthesizing 2,4,5-trimethoxyethylphenylketone intermediate of alpha-asarin | GUANGXI TRADITIONAL CHINESE MEDICAL UNIVERSITY | 2010-11-24 | — | — | CN | disclosed |
| CN-101492351-A | Process for producing asarin | YABANG CHEMICAL INDUSTRY GROUP (CN) | 2009-07-29 | — | — | CN | disclosed |
| CN-101195562-A | Novel method for synthesizing alpha-asarone | GUANGXI TRADITIONAL CHINESE ME (CN) | 2008-06-11 | — | — | CN | disclosed |
| EP-1444190-A1 | COMBRETASTATIN A-4 DERIVATIVES HAVING ANTINEOPLASTIC ACTIVITY | Cancer Research Technology Limited (GB) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003040077-A1 | COMBRETASTATIN A-4 DERIVATIVES HAVING ANTINEOPLASTIC ACTIVITY | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-05-15 | — | — | WO | disclosed |
| US-5952355-A | 1-ETHER-SUBSTITUTED PHENYL-3-INDOL-3-YL-2-PROPEN-1-ONE DERIVATIVES; ANTITUMOR AND -CARCINOGENIC AGENTS; IMMUNOSUPPRESSANTS; AUTOIMMUNE DISEASES; SIDE EFFECT REDUCTION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0770601-A1 | PROPENONE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |
| US-5103022-A | Reacting dl-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino -1-propanone with l-acetylphenylglycine to form corresponding diastereomeric salt, deposition, isolation of l-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino-1-propanone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5057535-A | Muscle relaxants | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0200942-A2 | New derivatives of an aminoketone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1986-11-12 | — | — | EP | disclosed |