Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 5/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648525 | 0.79 | MAPK1 (0.46) | KCNQ3KCNQ2KCNE1KCNQ1IDO1 | |
| SCHEMBL11679569 | 0.78 | NPC1 (0.50) | KDM1AMAOB | |
| SCHEMBL22390554 | 0.78 | KDM1A (0.49) | KDM1AMAOBKIF11ALOX5APFEN1 | |
| SCHEMBL9951105 | 0.78 | FEN1 (0.60) | KDM1AMAOBKIF11ALOX5APFEN1 | |
| SCHEMBL20203802 | 0.77 | CYP1A2 (0.48) | ALOX5APFEN1ALOX5 | |
| SCHEMBL1548905 | 0.77 | KDM1A (0.42) | KDM1AMAOBDYRK1ADYRK2KIF11 | |
| SCHEMBL1744141 | 0.77 | KIF11 (0.52) | KDM1AMAOBDYRK1ADYRK2KIF11 | |
| SCHEMBL28530523 | 0.76 | KIF11 (0.61) | KDM1AMAOBKIF11CASP1IDO1 | |
| SCHEMBL29690424 | 0.76 | KIF11 (0.61) | KDM1AMAOBKIF11CASP1IDO1 | |
| SCHEMBL4342508 | 0.75 | KIF11 (0.59) | KDM1AMAOBKIF11CASP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046763-A | INTERMEDIATE FOR ULTRAVIOLET LIGHT ABSORBERS | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |