Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528026 | 0.84 | TSHR (0.50) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL11683236 | 0.83 | TSHR (0.50) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL11682514 | 0.81 | TSHR (0.50) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL11684933 | 0.80 | TSHR (0.40) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL11682699 | 0.80 | TSHR (0.38) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL116802 | 0.72 | AR (0.44) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL2371854 | 0.72 | TSHR (0.58) | TSHRRORCPKMHPGDHDAC4 | |
| SCHEMBL909852 | 0.70 | TSHR (0.55) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL15914782 | 0.70 | TSHR (0.41) | TSHRRORC | |
| SCHEMBL9623205 | 0.69 | GABRA1 (0.39) | TSHRRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005156-A | Novel flame retardant compositions of matter | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-01-25 | — | — | US | disclosed |