Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898100 | 0.95 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL11648484 | 0.91 | MAOA (0.33) | SMN1; SMN2MAOAMAOBMAPTLMNA | |
| SCHEMBL11761945 | 0.77 | MAOA (0.35) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| Terephthalic Acid SCHEMBL11776560 | 0.75 | CYP2C8 (0.42) | ALDH1A1HPGDCA1CA9 | |
| SCHEMBL28500409 | 0.73 | MAOA (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL30413722 | 0.73 | MAOA (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL11741409 | 0.73 | CA1 (0.36) | ALDH1A1HPGDMAOAMAOBCA1 | |
| SCHEMBL30219513 | 0.71 | MAOA (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL2360787 | 0.71 | MAOA (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL28382443 | 0.71 | MAOA (0.33) | MAOAMAOBCA1CA9NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001188-A | Dimethyl 2,5-dibromoterephthalate esterification | STANDARD OIL COMPANY (INDIANA) (US) | 1977-01-04 | — | — | US | claimed |
| US-4001188-A | Dimethyl 2,5-dibromoterephthalate esterification | STANDARD OIL COMPANY (INDIANA) (US) | 1977-01-04 | — | — | US | disclosed |