SCHEMBL11683055

SCHEMBL11683055

O=C(O)Cc1ccc(OCCOc2ccc(CC(=O)O)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 1/20 0.61
TBXAS1 P24557 1/20 0.58
CA2 P00918 1/20 0.56
CAMK2A Q9UQM7 1/20 0.56
LMNA P02545 3/20 0.54
ALDH1A1 P00352 1/20 0.54
AKR1B1 P15121 1/20 0.54
LTB4R Q15722 3/20 0.54
LTB4R2 Q9NPC1 3/20 0.54
ALOX15 P16050 1/20 0.54
FFAR1 O14842 2/20 0.53
SRD5A2 P31213 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ABCC4 O15439 1/20 0.52
GAA P10253 1/20 0.52
TSHR P16473 1/20 0.52
PTGS1 P23219 1/20 0.52
HTT P42858 1/20 0.52
PKM P14618 1/20 0.52
KDM4E B2RXH2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11684213 0.94 PLA2G4B (0.69) PLA2G4BTBXAS1CA2CAMK2ALMNA
SCHEMBL11596764 0.91 NR4A2 (0.54) PLA2G4BTBXAS1LMNAALDH1A1LTB4R
SCHEMBL3331503 0.91 PLA2G4B (0.57) PLA2G4BTBXAS1LMNAALDH1A1LTB4R
SCHEMBL7713619 0.90 PLA2G4B (0.56) PLA2G4BTBXAS1CA2CAMK2ALMNA
SCHEMBL10728695 0.88 PLA2G4B (0.59) PLA2G4BTBXAS1LMNAALDH1A1LTB4R
SCHEMBL7660622 0.88 PLA2G4B (0.55) PLA2G4BTBXAS1CA2CAMK2ALMNA
SCHEMBL11597039 0.88 PLA2G4B (0.59) PLA2G4BTBXAS1CA2CAMK2ALMNA
SCHEMBL1443020 0.88 LMNA (0.70) PLA2G4BTBXAS1LMNAALDH1A1LTB4R
SCHEMBL8767652 0.88 LTB4R (0.63) PLA2G4BLMNAAKR1B1LTB4RLTB4R2
SCHEMBL926518 0.88 LTA4H (0.58) PLA2G4BTBXAS1CA2CAMK2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4057597-A Block-type aryl copolyesters and filaments based on these copolyesters RHONE-POULENC-TEXTILE (FR) 1977-11-08 US disclosed