Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162418 | 0.91 | PLA2G4B (0.59) | PLA2G4BALDH1A1TBXAS1LMNAPTPN11 | |
| SCHEMBL11683055 | 0.90 | PLA2G4B (0.61) | PLA2G4BGAAALDH1A1TBXAS1LMNA | |
| SCHEMBL11684213 | 0.88 | PLA2G4B (0.69) | PLA2G4BALDH1A1TBXAS1LMNAPTPN11 | |
| SCHEMBL2628195 | 0.87 | PLA2G4B (0.55) | PLA2G4BALDH1A1TBXAS1LMNALTB4R | |
| SCHEMBL2628191 | 0.87 | PLA2G4B (0.55) | PLA2G4BALDH1A1TBXAS1LMNALTB4R | |
| SCHEMBL11155906 | 0.84 | CA2 (0.54) | PLA2G4BGAATBXAS1LMNAABCC4 | |
| SCHEMBL18687708 | 0.83 | ALOX15 (0.60) | PLA2G4BALDH1A1TBXAS1LMNAHTT | |
| SCHEMBL1443020 | 0.83 | LMNA (0.70) | PLA2G4BALDH1A1TBXAS1LMNAPTPN11 | |
| SCHEMBL926518 | 0.83 | LTA4H (0.58) | PLA2G4BALDH1A1TBXAS1LMNALTB4R | |
| SCHEMBL7660622 | 0.83 | PLA2G4B (0.55) | PLA2G4BALDH1A1TBXAS1LMNALTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107474024-B | Glutaminase inhibitor and composition and application thereof | 北京赛林泰医药技术有限公司 | 2022-12-13 | — | — | CN | disclosed |
| US-6365172-B1 | SELF-REINFORCED BIOABSORBABLE DEVICE COMPRISED OF FUSED OR SINTERED FIBERS MADE FROM BIOABSORBABLE POLYMER COMPRISING SPECIFIED POLYESTERAMIDE | BIOAMIDE, INC. | 2002-04-02 | — | — | US | disclosed |
| US-6120788-A | Bioabsorbable triglycolic acid poly(ester-amide)s | BIOAMIDE, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| US-4748169-A | FLUOROPOLYMERS, PRINTED CIRCUITS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1988-05-31 | — | — | US | disclosed |