Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11687677 | 0.99 | POLB (0.51) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL11685445 | 0.91 | MEN1 (0.47) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL11686069 | 0.89 | OPRL1 (0.52) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL11690706 | 0.81 | OPRL1 (0.51) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL7511281 | 0.77 | OPRL1 (0.57) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| Hydrochloric Acid SCHEMBL6543173 | 0.76 | POLB (0.58) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL16076720 | 0.75 | OPRL1 (0.58) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL6132006 | 0.74 | CYP2D6 (0.46) | OPRL1POLBCYP2D6CYP3A4HSD17B10 | |
| SCHEMBL22050089 | 0.73 | OPRL1 (0.55) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| Dimethylamine SCHEMBL11444308 | 0.73 | NPFFR1 (0.43) | OPRL1POLBCYP2D6CCR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018922-A | NEUROLEPTICS, ANALGESICS, SPASMOLYTICS, AND ANTIHISTAMINES | ROUSSEL-UCLAF (FR) | 1977-04-19 | — | — | US | disclosed |