Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687492 | 0.86 | PRKCA (0.44) | SIRT2PRKCALMNA | |
| SCHEMBL30732593 | 0.84 | SIRT2 (0.47) | SIRT2PRKCA | |
| SCHEMBL3916209 | 0.77 | SIRT2 (0.42) | SIRT2ALDH1A1HPGDLMNATSHR | |
| SCHEMBL18134613 | 0.77 | SIRT2 (0.92) | SIRT2PRKCA | |
| SCHEMBL26566738 | 0.75 | PRKCA (0.54) | SIRT2PRKCA | |
| SCHEMBL11188189 | 0.73 | SIRT2 (0.39) | SIRT2ALDH1A1HPGDLMNATSHR | |
| SCHEMBL11220265 | 0.73 | SIRT2 (1.00) | SIRT2PRKCA | |
| Tanikolide SCHEMBL9902905 | 0.73 | SIRT2 (1.00) | SIRT2PRKCA | |
| SCHEMBL18134616 | 0.73 | SIRT2 (1.00) | SIRT2PRKCA | |
| SCHEMBL18134618 | 0.73 | SIRT2 (1.00) | SIRT2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054569-A | CNS DEPRESSANTS, ANTICONVULSIVES, ANTIINFLAMMATORY | AYERST MCKENNA & HARRISON LTD. (CA) | 1977-10-18 | — | — | US | disclosed |
| US-3985751-A | CNS DEPRESSANTS, ANTICONVULSANT AND ANTIINFLAMMATORY AGENTS | AYERST MCKENNA AND HARRISON LTD. (CA) | 1976-10-12 | — | — | US | disclosed |