Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.56 |
| ▸ | MAOA | P21397 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683065 | 1.00 | MAOB (0.56) | MAOBMAOAALDH1A1MAPTLMNA | |
| SCHEMBL11686192 | 0.81 | MAOB (0.58) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL11686198 | 0.81 | MAOB (0.58) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL11686567 | 0.81 | MAOB (0.53) | MAOBMAOAALDH1A1MAPTMEN1 | |
| SCHEMBL11686561 | 0.81 | MAOB (0.53) | MAOBMAOAALDH1A1MAPTMEN1 | |
| Formic Acid SCHEMBL11683586 | 0.78 | MAOB (0.54) | MAOBMAOAALDH1A1MAPTLMNA | |
| SCHEMBL11684295 | 0.75 | MAOB (0.56) | MAOBMAOAMEN1KMT2AUSP2 | |
| SCHEMBL11684299 | 0.75 | MAOB (0.56) | MAOBMAOAMEN1KMT2AUSP2 | |
| SCHEMBL11687872 | 0.75 | KMT2A (0.60) | MAOBMAOAALDH1A1MAPTLMNA | |
| SCHEMBL11687864 | 0.75 | KMT2A (0.60) | MAOBMAOAALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006234-A | Substituted 2-benzofuranyl propenones as anti-tubercular agents | AMERICAN CYANAMID COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-3931157-A | ANTITUBERCULAR | AMERICAN CYANAMID COMPANY (US) | 1976-01-06 | — | — | US | disclosed |