Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.58 |
| ▸ | MAOA | P21397 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686198 | 1.00 | MAOB (0.58) | MAOBMAOAMEN1USP2KMT2A | |
| Formic Acid SCHEMBL11683586 | 0.96 | MAOB (0.54) | MAOBMAOAMEN1USP2KMT2A | |
| SCHEMBL11684299 | 0.89 | MAOB (0.56) | MAOBMAOAMEN1USP2KMT2A | |
| SCHEMBL11684295 | 0.89 | MAOB (0.56) | MAOBMAOAMEN1USP2KMT2A | |
| SCHEMBL11683808 | 0.85 | TAS1R3 (0.45) | MAOBNPC1RAB9AF12CA12 | |
| SCHEMBL11683812 | 0.85 | TAS1R3 (0.45) | MAOBNPC1RAB9AF12CA12 | |
| SCHEMBL11683581 | 0.85 | MAOB (0.59) | MAOBMAOAMEN1KMT2ANPC1 | |
| SCHEMBL11684813 | 0.85 | MAOB (0.56) | MAOBMAOAMEN1KMT2ANPC1 | |
| SCHEMBL11683578 | 0.85 | MAOB (0.59) | MAOBMAOAMEN1KMT2ANPC1 | |
| SCHEMBL11684810 | 0.85 | MAOB (0.56) | MAOBMAOAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006234-A | Substituted 2-benzofuranyl propenones as anti-tubercular agents | AMERICAN CYANAMID COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-3931157-A | ANTITUBERCULAR | AMERICAN CYANAMID COMPANY (US) | 1976-01-06 | — | — | US | disclosed |