Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL28432808 | 0.95 | LMNA (0.48) | LMNAALDH1A1ALOX15HSD17B10OR51E2 | |
| Glycerin SCHEMBL29380685 | 0.93 | LMNA (0.56) | LMNAALDH1A1ALOX15HSD17B10OR51E2 | |
| Glycerin SCHEMBL4946329 | 0.93 | LMNA (0.56) | LMNAALDH1A1ALOX15HSD17B10OR51E2 | |
| Glycerin SCHEMBL29486376 | 0.93 | LMNA (0.56) | LMNAALDH1A1ALOX15HSD17B10OR51E2 | |
| Glycerin SCHEMBL733112 | 0.93 | LMNA (0.56) | LMNAALDH1A1ALOX15HSD17B10OR51E2 | |
| Glycerin SCHEMBL25331899 | 0.93 | LMNA (0.56) | LMNAALDH1A1ALOX15HSD17B10OR51E2 | |
| Glycerin SCHEMBL3370803 | 0.93 | LMNA (0.56) | LMNAALDH1A1ALOX15HSD17B10OR51E2 | |
| Glycerin SCHEMBL31041752 | 0.93 | LMNA (0.56) | LMNAALDH1A1ALOX15HSD17B10OR51E2 | |
| Glycerin SCHEMBL116158 | 0.93 | LMNA (0.56) | LMNAALDH1A1ALOX15HSD17B10OR51E2 | |
| Glycerin SCHEMBL29372798 | 0.93 | LMNA (0.56) | LMNAALDH1A1ALOX15HSD17B10OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054722-A | PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-18 | — | — | US | disclosed |